{
  "id": "medical/iv-pump-rate-calculation-error",
  "signature": "AI miscalculates IV pump rate for dopamine infusion using wrong concentration factor, leading to potential overdose",
  "signature_zh": "AI使用错误的浓度系数计算多巴胺输注的静脉泵速率，导致潜在过量用药",
  "regex": "(?:dopamine|dobutamine|norepinephrine|epinephrine)\\s+(?:infusion|drip|rate|calculation|pump)\\s*(?:error|wrong|miscalculat)",
  "domain": "medical",
  "category": "data_error",
  "subcategory": null,
  "root_cause": "Dopamine is typically supplied as 400 mg/250 mL (1.6 mg/mL) or 800 mg/250 mL (3.2 mg/mL), but AI assumes a standard concentration of 1 mg/mL, causing a 60% or 220% error in infusion rate calculation for common dosing (5-20 mcg/kg/min).",
  "root_cause_type": "generic",
  "root_cause_zh": "多巴胺通常以400毫克/250毫升（1.6毫克/毫升）或800毫克/250毫升（3.2毫克/毫升）供应，但AI假设标准浓度为1毫克/毫升，导致常见剂量（5-20微克/千克/分钟）的输注速率计算出现60%或220%的错误。",
  "versions": [
    {
      "version": "Alaris PCU v6.0",
      "introduced": null,
      "deprecated": null,
      "removed": null,
      "behavior_change": null,
      "status": "active"
    },
    {
      "version": "Baxter Sigma Spectrum v8.1",
      "introduced": null,
      "deprecated": null,
      "removed": null,
      "behavior_change": null,
      "status": "active"
    },
    {
      "version": "Braun Infusomat Space v2.5",
      "introduced": null,
      "deprecated": null,
      "removed": null,
      "behavior_change": null,
      "status": "active"
    }
  ],
  "os_specific": {},
  "dead_ends": [
    {
      "action": "",
      "why_fails": "Pump programming is often correct; the error is in the concentration factor used in the calculation, not the pump entry itself",
      "fail_rate": 0.7,
      "condition": "",
      "sources": []
    },
    {
      "action": "",
      "why_fails": "This concentration is rarely used in ICU; standard is 250 mL bags; using wrong volume compounds the error",
      "fail_rate": 0.6,
      "condition": "",
      "sources": []
    },
    {
      "action": "",
      "why_fails": "The dose itself may be correct, but the rate-to-concentration conversion is flawed; proportional adjustment propagates the error",
      "fail_rate": 0.55,
      "condition": "",
      "sources": []
    }
  ],
  "workarounds": [
    {
      "action": "Always verify IV drug concentration from pharmacy label before programming pump; use a standardized calculator like 'MedCalc' or 'MDCalc' that requires both drug amount and diluent volume",
      "success_rate": 0.9,
      "how": "Always verify IV drug concentration from pharmacy label before programming pump; use a standardized calculator like 'MedCalc' or 'MDCalc' that requires both drug amount and diluent volume",
      "condition": "",
      "sources": []
    },
    {
      "action": "Implement a two-nurse verification protocol: one calculates, the other independently recalculates using a different method (e.g., infusion rate = (dose x weight x 60) / concentration)",
      "success_rate": 0.85,
      "how": "Implement a two-nurse verification protocol: one calculates, the other independently recalculates using a different method (e.g., infusion rate = (dose x weight x 60) / concentration)",
      "condition": "",
      "sources": []
    },
    {
      "action": "Use smart pump drug library (e.g., Alaris Guardrails) that auto-calculates rate based on selected drug and concentration; override only after double-check",
      "success_rate": 0.95,
      "how": "Use smart pump drug library (e.g., Alaris Guardrails) that auto-calculates rate based on selected drug and concentration; override only after double-check",
      "condition": "",
      "sources": []
    }
  ],
  "workarounds_zh": [
    "Always verify IV drug concentration from pharmacy label before programming pump; use a standardized calculator like 'MedCalc' or 'MDCalc' that requires both drug amount and diluent volume",
    "Implement a two-nurse verification protocol: one calculates, the other independently recalculates using a different method (e.g., infusion rate = (dose x weight x 60) / concentration)",
    "Use smart pump drug library (e.g., Alaris Guardrails) that auto-calculates rate based on selected drug and concentration; override only after double-check"
  ],
  "transition_graph": {
    "leads_to": [],
    "preceded_by": [],
    "frequently_confused_with": []
  },
  "official_doc_url": "https://www.uptodate.com/contents/dopamine-drug-information",
  "official_doc_section": null,
  "error_code": "DOPA-CONC-ERR-001",
  "verification_tier": "ai_generated",
  "confidence": 0.88,
  "fix_success_rate": 0.9,
  "resolvable": "true",
  "first_seen": "2024-01-20",
  "last_confirmed": "2024-06-01",
  "last_updated": "2024-06-01",
  "evidence_count": 1,
  "tags": [],
  "locale": "en",
  "aliases": []
}