{
  "id": "medical/medication-list-interpretation",
  "signature": "AI misinterprets a medication list by translating 'Tylenol #3' as acetaminophen 300 mg with codeine 30 mg without flagging the codeine component for pediatric patients under 12",
  "signature_zh": "AI将‘Tylenol #3’误解为对乙酰氨基酚300毫克和可待因30毫克，未对12岁以下儿童标记可待因成分",
  "regex": "Tylenol #3|acetaminophen.*codeine|codeine.*pediatric",
  "domain": "medical",
  "category": "data_error",
  "subcategory": null,
  "root_cause": "'Tylenol #3' is a brand name for acetaminophen 300 mg + codeine 30 mg; AI fails to recognize the codeine component and its FDA black box warning for children under 12 years after tonsillectomy or for any child under 18 with respiratory risk.",
  "root_cause_type": "generic",
  "root_cause_zh": "‘Tylenol #3’是对乙酰氨基酚300毫克和可待因30毫克的品牌名；AI未能识别可待因成分及其FDA黑框警告——12岁以下儿童扁桃体切除术后或任何18岁以下有呼吸风险的儿童禁用。",
  "versions": [],
  "os_specific": {},
  "dead_ends": [
    {
      "action": "",
      "why_fails": "The '#3' suffix specifically indicates codeine 30 mg per tablet; interpreting it as quantity leads to missing the opioid component.",
      "fail_rate": 0.9,
      "condition": "",
      "sources": []
    },
    {
      "action": "",
      "why_fails": "Codeine is a prodrug metabolized to morphine; ultra-rapid metabolizers (CYP2D6) can have fatal respiratory depression. FDA warns against all codeine use in children under 12.",
      "fail_rate": 0.95,
      "condition": "",
      "sources": []
    },
    {
      "action": "",
      "why_fails": "Omits the opioid component entirely, leading to under-treatment of pain or missed drug interaction warnings.",
      "fail_rate": 0.85,
      "condition": "",
      "sources": []
    }
  ],
  "workarounds": [
    {
      "action": "Parse 'Tylenol #3' as a fixed combination: acetaminophen 300 mg + codeine 30 mg. Flag for pediatric patients under 12 years: 'Codeine is contraindicated in children under 12 years due to risk of respiratory depression.' Example: if patient is 8 years old, do not recommend this medication.",
      "success_rate": 0.9,
      "how": "Parse 'Tylenol #3' as a fixed combination: acetaminophen 300 mg + codeine 30 mg. Flag for pediatric patients under 12 years: 'Codeine is contraindicated in children under 12 years due to risk of respiratory depression.' Example: if patient is 8 years old, do not recommend this medication.",
      "condition": "",
      "sources": []
    },
    {
      "action": "Use a medication database lookup (e.g., RxNorm, DrugBank) to resolve brand names into active ingredients with warnings. For any codeine-containing product, automatically check patient age and surgical history.",
      "success_rate": 0.85,
      "how": "Use a medication database lookup (e.g., RxNorm, DrugBank) to resolve brand names into active ingredients with warnings. For any codeine-containing product, automatically check patient age and surgical history.",
      "condition": "",
      "sources": []
    }
  ],
  "workarounds_zh": [
    "Parse 'Tylenol #3' as a fixed combination: acetaminophen 300 mg + codeine 30 mg. Flag for pediatric patients under 12 years: 'Codeine is contraindicated in children under 12 years due to risk of respiratory depression.' Example: if patient is 8 years old, do not recommend this medication.",
    "Use a medication database lookup (e.g., RxNorm, DrugBank) to resolve brand names into active ingredients with warnings. For any codeine-containing product, automatically check patient age and surgical history."
  ],
  "transition_graph": {
    "leads_to": [],
    "preceded_by": [],
    "frequently_confused_with": []
  },
  "official_doc_url": "https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-restricts-use-prescription-codeine-pain-and-cough-medicines-children",
  "official_doc_section": null,
  "error_code": "MED_LIST_INTERP_COD",
  "verification_tier": "ai_generated",
  "confidence": 0.87,
  "fix_success_rate": 0.78,
  "resolvable": "true",
  "first_seen": "2024-01-10",
  "last_confirmed": "2024-06-01",
  "last_updated": "2024-06-01",
  "evidence_count": 1,
  "tags": [],
  "locale": "en",
  "aliases": []
}