AI将‘Tylenol #3’误解为对乙酰氨基酚300毫克和可待因30毫克，未对12岁以下儿童标记可待因成分
AI misinterprets a medication list by translating 'Tylenol #3' as acetaminophen 300 mg with codeine 30 mg without flagging the codeine component for pediatric patients under 12
ID: medical/medication-list-interpretation
根因分析
‘Tylenol #3’是对乙酰氨基酚300毫克和可待因30毫克的品牌名；AI未能识别可待因成分及其FDA黑框警告——12岁以下儿童扁桃体切除术后或任何18岁以下有呼吸风险的儿童禁用。
English
'Tylenol #3' is a brand name for acetaminophen 300 mg + codeine 30 mg; AI fails to recognize the codeine component and its FDA black box warning for children under 12 years after tonsillectomy or for any child under 18 with respiratory risk.
官方文档
https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-restricts-use-prescription-codeine-pain-and-cough-medicines-children解决方案
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Parse 'Tylenol #3' as a fixed combination: acetaminophen 300 mg + codeine 30 mg. Flag for pediatric patients under 12 years: 'Codeine is contraindicated in children under 12 years due to risk of respiratory depression.' Example: if patient is 8 years old, do not recommend this medication.
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Use a medication database lookup (e.g., RxNorm, DrugBank) to resolve brand names into active ingredients with warnings. For any codeine-containing product, automatically check patient age and surgical history.
无效尝试
常见但无效的做法:
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90% 失败
The '#3' suffix specifically indicates codeine 30 mg per tablet; interpreting it as quantity leads to missing the opioid component.
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95% 失败
Codeine is a prodrug metabolized to morphine; ultra-rapid metabolizers (CYP2D6) can have fatal respiratory depression. FDA warns against all codeine use in children under 12.
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85% 失败
Omits the opioid component entirely, leading to under-treatment of pain or missed drug interaction warnings.